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Online Tool
[ English / Japanese ]
NOTES
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Sources of the synaptic connectivity are the following data files in the database[3].
(a) synapse_WF.txt:
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somatic nervous system presented in the figures in the paper[1]
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(b) synapse_WT.txt:
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somatic nervous system presented in the tables in the paper[1]
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(c) White_Text.txt:
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synaptic connectivity of PDA and PDB neuron classes presented in the text (pp.215-216) in the paper[1]
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(d) synapse_AF.txt:
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pharyngeal nervous system presented in the figures in paper[2]
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Several ambiguous or questionable
descriptions are found in the original papers[1,2].
Different interpretation and handling of these descriptions
might cause a difference in the computed number of synapses.
For this reason,
these descriptions are not improved in the database[3] (the above four data files).
Instead of improvement,
the comment index is attached to the corresponding data.
It is the work of users to improve these descriptions according to their own policy.
The details of improvement in this tool is presented in
this page.
 
analysis of anatomical data in the original papers[1,2] and improvement in this tool
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In addition, there is a problem that the connectivity data in the file (a)
and that in (b) are not complementary each other [White, personal communication].
Therefore data mergence of them would lead to double-counting of the synapses.
In this tool, the synaptic connectivity computed with the file (a) and
that with (b) are displayed separately.
If the number of synapses shown in this tool is different from
that in other synaptic connectivity database,
the difference comes from the above mentioned reasons.
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If the connection data is consistent,
the number of synapses which "A" neuron sends to "B" neuron (#Send(A --> B))
is equal to
the number of synapses which "B" neuron receive from "A" neuron (#Receive(B <-- A)),
that is, #Send(A --> B) = #Receive(B <-- A).
The anatomical data in the paper[1] almost satisfies this relation, however,
there are a few inconsistent data.
In such cases, this tool displays only the greater number of them, that is,
    the number of synapses from "A" to "B" neuron = MAX( #Send(A --> B), #Receive(B <-- A) )
REFERENCES
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J. G. White, E. Southgate, J. N. Thomson and S. Brenner,
"The Structure of the Nervous System of the Nematode Caenorhabditis elegans",
Phil. Trans. R. Soc. London, B 314 (1986) 1-340.
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D. G. Albertson and J. N. Thomson,
"The Pharynx of Caenorhabditis elegans",
Phil. Trans. R. Soc. London, B 275 (1976) 299-325.
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K. Oshio, Y. Iwasaki, S. Morita, Y. Osana, S. Gomi,
E. Akiyama, K. Omata, K. Oka and K. Kawamura,
"Database of Synaptic Connectivity of C. elegans
for Computation",
Technical Report of CCeP, Keio Future, No.3, (2003) Keio University.
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